NAD+ Therapy
NAD+ THERAPY COST: WHAT YOU'LL ACTUALLY PAY
The cost of NAD+ therapy varies wildly -- from $25 to $1,500 per session depending on delivery method, clinic type, and geographic market. This guide breaks down what you'll actually pay and why the price differences are so dramatic.
Medically reviewed by Missy Zammichieli, DNP, APRN, FNP-BC ยท Published March 25, 2026
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NAD+ COST BY DELIVERY METHOD
NAD+ therapy isn't one thing. The delivery method determines the cost more than anything else. Here's the full landscape:
| Method | Cost Per Session | 3-Month Protocol | Bioavailability | Time Per Session |
|---|---|---|---|---|
| IV Drip | $400-1,500 | $2,400-9,000 | Variable (rapid clearance debated) | 2-4 hours |
| SubQ Injection (clinic) | $25-200 | $300-2,400 | Direct to tissue | 5 minutes |
| IM Injection (clinic) | $50-250 | $600-3,000 | Direct to tissue | 5 minutes |
| Oral NMN Supplement | $40-80/month | $120-240 | Low (gut absorption + conversion) | Daily pill |
| Oral NR Supplement | $30-60/month | $90-180 | Low (similar to NMN) | Daily pill |
| NAD+ Patches | $50-150/month | $150-450 | Unknown (limited data) | Continuous |
| Moonshot Medical | $60/shot | $480-720 | Direct SubQ delivery | 5 minutes |
Key takeaway: The molecule is the same. The delivery method and clinic overhead determine the price. A $1,500 IV drip and a $60 subcutaneous injection both deliver NAD+ to your bloodstream. The IV just takes 2-4 hours longer and requires significantly more clinical resources. For a deeper look at how NAD+ works and why delivery method matters, read our comprehensive NAD+ guide.
WHAT DRIVES THE COST DIFFERENCE
A 25x price difference between the cheapest and most expensive NAD+ options isn't random. Four factors explain almost all of it:
Delivery Method
This is the biggest cost driver. IV drips require a registered nurse to place and monitor the catheter for 2-4 hours. That means dedicated clinical space, IV supplies (catheter, tubing, saline, drip bags), and 2-4 hours of staff time per patient. A subcutaneous injection uses an insulin syringe, takes 5 minutes, and can be administered by any trained medical staff. The clinical overhead difference is enormous -- and it flows directly into the price you pay.
Clinic Type
Med spas and IV lounges price for the experience -- leather recliners, ambient lighting, complimentary beverages. That ambiance costs money, and it gets baked into the per-session fee. Medical clinics that offer NAD+ as one component of a broader optimization program price based on product cost plus clinical oversight, without the wellness theater markup. The NAD+ molecule doesn't know whether the room has Edison bulbs or fluorescent lights.
Protocol Length
Per-session cost is a misleading metric if you don't factor in the full protocol. NAD+ therapy typically involves a loading phase (2x/week for 2-4 weeks) followed by ongoing maintenance (weekly to monthly). A $60 injection twice a week for a month is $480. A $750 IV drip once a week for a month is $3,000. Total protocol cost over 3-6 months tells you what you'll actually spend -- not the per-session number on the menu board.
Geographic Market
NAD+ IV drips in Manhattan or Beverly Hills run $1,000-1,500 per session. The same drip in suburban Chicago costs $300-600. The product is identical. Real estate costs, staffing costs, and local market willingness to pay explain the delta. Suburban clinics like Moonshot Medical in Park Ridge operate with lower overhead than downtown Chicago or coastal markets, and pass that savings through to pricing.
TYPICAL NAD+ PROTOCOL COSTS OVER TIME
NAD+ therapy is not a one-and-done treatment. It's an ongoing protocol. Here's what a full year looks like at two different price points:
Moonshot Medical ($60/shot)
Typical IV Clinic ($750/session)
The math: A patient doing NAD+ at Moonshot spends roughly $2,000-3,400 in Year 1. The same patient doing IV NAD+ at a typical clinic spends $15,000-24,000 for the same year. That's a 7-8x cost difference for NAD+ delivered to the same bloodstream. The molecule doesn't care how it got there.
INSURANCE, HSA & FSA
NAD+ therapy is not covered by insurance. It is not FDA-approved for any specific indication, so no insurer -- commercial, Medicare, or Medicaid -- will reimburse for it. This applies regardless of delivery method: IV, SubQ, IM, or oral. If a clinic tells you otherwise, verify carefully before assuming coverage.
HSA and FSA accounts are a different story. These pre-tax funds can be used for medical expenses that are prescribed by a licensed provider for a diagnosed condition. If your NAD+ therapy is prescribed for a diagnosed condition -- fatigue, metabolic dysfunction, documented NAD+ deficiency -- it may qualify for HSA/FSA reimbursement. This is a gray area that depends on your specific plan administrator's interpretation. Check before assuming.
Moonshot Medical provides superbills upon request. A superbill is a detailed receipt with diagnosis codes, procedure codes, and provider information that you can submit to your HSA/FSA administrator or insurance for potential reimbursement.
Practical tip: If you're using HSA/FSA funds, the $60 per injection price point at Moonshot means your pre-tax dollars go 7-8x further than they would at an IV clinic charging $400-750 per session. Same therapy, same tax advantage, dramatically more sessions per dollar.
NAD+ COSTS IN THE CHICAGO AREA
If you're comparing NAD+ therapy options in the greater Chicago area, here's what the market looks like:
| Clinic | Location | Price | Delivery |
|---|---|---|---|
| GlobalClinic | Niles, IL | $299-599/session | IV Drip |
| MD Infusions | Northbrook, IL | $299-599/session | IV Drip |
| Chicago Aesthetics | Chicago, IL | $250+/session | IV Drip |
| Freeze & Float | Chicago, IL | $350-660/session | IV Drip |
| Moonshot Medical | Park Ridge, IL | $60/shot | SubQ Injection |
Important context: Most Chicago-area competitors offer IV drips. Moonshot offers subcutaneous injections. These are different delivery methods with different clinical profiles. IV provides higher peak plasma concentrations over 2-4 hours. SubQ provides direct tissue delivery in 5 minutes. The price difference reflects the overhead difference, not a difference in the NAD+ molecule itself. For a full comparison of delivery methods and bioavailability, see our NAD+ vs NMN comparison.
WHY MOONSHOT IS $60
We're not running a loss leader. We're not cutting corners. The price is $60 because our cost structure makes $60 a sustainable, profitable price point. Here's why:
SubQ, Not IV
We use subcutaneous injection, not IV drips. This eliminates 2-4 hours of chair time, continuous nursing supervision, and all IV supplies (catheter, tubing, saline bags, drip stands). The appointment takes 5 minutes. Lower overhead means lower pricing without lower margins.
Medical Clinic, Not Wellness Lounge
We're a medical clinic that provides NAD+ therapy alongside hormone optimization, lab work, and peptide therapy. We don't charge for ambiance. No leather recliners, no cucumber water, no Edison bulbs. You're paying for the molecule and the clinical oversight.
Part of an Ecosystem
NAD+ injections are one component of a broader optimization platform -- not a standalone cash-grab service. Most of our NAD+ patients are also doing hormone therapy, bloodwork monitoring, or peptide protocols. The integrated approach means NAD+ doesn't need to carry the full revenue weight of the patient relationship.
Included for Members
Hormone optimization members receive 1 vitamin injection per month included in their membership. This means many of our NAD+ patients are already in the clinic for their optimization visit. Marginal cost per injection is low. We pass that efficiency through to pricing.
Not a claim about superiority: We're not saying SubQ is "better" than IV. They're different delivery methods. IV provides higher peak plasma concentrations and may be preferred for specific clinical situations. SubQ provides direct tissue delivery, takes 5 minutes, and costs a fraction of the price. For most patients pursuing NAD+ for energy, recovery, and anti-aging benefits, SubQ at $60 is a rational choice. For a deeper understanding of how NAD+ works at the cellular level, read our full NAD+ guide.
NAD+ THERAPY COST FAQ
How much does NAD+ therapy cost at Moonshot?
NAD+ injections at Moonshot Medical in Park Ridge, IL cost $60 per subcutaneous injection. A typical loading phase (8 sessions over 4 weeks) costs $480, and monthly maintenance runs $120-240 depending on frequency. Hormone optimization members receive 1 vitamin injection per month included in their membership.
Is NAD+ therapy worth the cost?
It depends on the delivery method and your goals. IV NAD+ at $400-1,500 per session is hard to justify for most people given the time commitment and the unclear bioavailability advantage over cheaper methods. SubQ injections at $60 per shot offer a much better cost-to-benefit ratio for patients experiencing fatigue, slow recovery, brain fog, or age-related energy decline. The value improves further when NAD+ is part of a broader optimization protocol with hormone therapy and lab monitoring.
Why is IV NAD+ so much more expensive than injections?
IV NAD+ requires 2-4 hours of chair time, continuous nurse supervision, IV supplies (catheter, tubing, saline), and dedicated clinical space. A subcutaneous injection takes 5 minutes and requires an insulin syringe. The clinical overhead difference is massive, and IV lounges also add markups for the experience and ambiance. The NAD+ molecule itself costs roughly the same regardless of how it's delivered.
Does insurance cover NAD+ therapy?
No. NAD+ therapy is not FDA-approved for any specific indication, so insurance does not cover it regardless of delivery method. HSA and FSA funds may be eligible if the therapy is prescribed by a medical provider for a diagnosed condition. Check with your plan administrator. Moonshot Medical provides superbills upon request.
How many NAD+ sessions will I need?
A typical protocol starts with a loading phase of 2 sessions per week for 4 weeks (8 sessions total), then transitions to maintenance at 1-2 sessions per week or biweekly. Some patients do well on monthly maintenance after the initial loading phase. Your provider will adjust based on your response, lab markers, and goals. At $60 per shot, the loading phase costs $480 and monthly maintenance runs $120-240.
Can I use my HSA or FSA for NAD+ injections?
Potentially. HSA and FSA funds can be used for medical expenses prescribed by a provider. If your NAD+ therapy is prescribed for a diagnosed condition (fatigue, metabolic dysfunction, etc.), it may qualify. Eligibility varies by plan, so check with your plan administrator before assuming coverage. Moonshot provides superbills that you can submit for reimbursement.
GET NAD+ AT A FRACTION OF THE COST
$60 per shot. 5 minutes per visit. No IV chair time, no wellness lounge markup. Just NAD+ delivered by a medical team that knows what they're doing.
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