Peptide Therapy
Which Peptide Should I Take?
Peptide therapy is not one-size-fits-all. Different peptides target completely different biological pathways. This guide helps you narrow down which one fits your goals, your budget, and your body.
Medically reviewed by Missy Zammichieli, DNP, APRN, FNP-BC · April 2, 2026
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WHY CHOOSING THE RIGHT PEPTIDE MATTERS
Interest in peptide therapy has grown significantly over the past several years. More patients are asking about peptides, more clinics are offering them, and more content is being published about their benefits. The problem is that most of that content treats peptides as interchangeable. They are not.
A peptide designed to rebuild tendon tissue operates through a completely different mechanism than one designed to improve skin elasticity or one that addresses sexual dysfunction. Choosing the wrong peptide is not dangerous, but it is a waste of time and money. You will spend months on a compound that was never designed to address your actual problem.
This guide is structured around the question patients actually ask: "I have [this goal]. Which peptide should I take?" We will walk through each major therapeutic category, compare the options side by side, cover pricing and stacking, and give you a framework for making a decision with your provider.
If you want to skip the reading and get a personalized recommendation, take our free 2-minute peptide quiz.
DECISION FRAMEWORK BY GOAL
Start with what you are trying to fix. Each goal maps to a different set of peptides that target the relevant biological pathways.
Injury Recovery (Tendons, Ligaments, Joints)
This is the most common reason patients start peptide therapy. You have a tendon injury, a ligament that will not heal, joint pain that physical therapy has not resolved, or a surgical recovery that is stalling.
BPC-157 ($250/month) is the most studied peptide for localized tissue repair. Derived from a protective protein in human gastric juice, it promotes angiogenesis (new blood vessel formation) and upregulates growth factors directly at injury sites. Over 100 published studies document its effects on tendon, ligament, muscle, and nerve tissue healing. Best for: specific, localized injuries you can inject near.
TB-500 ($250/month) works systemically through a different mechanism. It upregulates actin, a protein involved in cell structure and migration, allowing repair cells to reach damaged tissue more effectively. Best for: widespread inflammation, multiple injury sites, or situations where you need systemic tissue repair rather than targeted healing.
Wolverine Blend ($375/month) combines BPC-157 and TB-500 in a single formulation. You get the localized repair of BPC-157 and the systemic reach of TB-500. Best for: patients with significant injuries who want comprehensive coverage, or athletes who need both targeted and systemic recovery.
Gut Healing (IBS, Leaky Gut, GI Inflammation)
BPC-157 ($250/month) is the clear choice here. This peptide was originally isolated from a gastric protective protein, meaning it evolved specifically to protect and repair the gut lining. Research shows it accelerates healing of intestinal mucosal damage, reduces gut inflammation, and promotes restoration of gut barrier integrity. It can be administered subcutaneously (systemically) or in some protocols is taken orally for direct GI exposure.
If your gut issues coexist with other inflammatory conditions or food sensitivities, stacking BPC-157 with NAD+ ($60/shot) supports the cellular energy your gut lining needs to repair.
Skin Quality and Anti-Aging
GHK-Cu ($175/month) is a copper-binding peptide that stimulates collagen and elastin synthesis, tightens skin, reduces fine lines, and improves overall skin texture and tone. It works by activating genes involved in tissue remodeling and has additional anti-inflammatory and antioxidant properties. Best for: patients focused primarily on skin quality, elasticity, and visible signs of aging.
Glow Stack ($400/month) is a comprehensive anti-aging formulation that combines multiple peptides targeting different aspects of skin health and aging. Best for: patients who want a full-spectrum approach to anti-aging rather than targeting a single pathway.
Athletic Performance and Body Composition
Athletes have multiple options depending on what they are trying to optimize.
Wolverine Blend ($375/month) is the top choice for athletes who train hard and accumulate microtrauma. The BPC-157 and TB-500 combination accelerates recovery between sessions and addresses chronic overuse injuries that limit training volume.
Sermorelin ($250/month) is a growth hormone releasing hormone (GHRH) analog that stimulates your pituitary gland to produce and release more growth hormone. Growth hormone drives body composition changes (more lean mass, less body fat), faster recovery, and deeper sleep. Unlike exogenous growth hormone, Sermorelin works through your body's own feedback loops. Best for: patients focused on body composition, sleep quality, and long-term performance optimization.
NAD+ ($60/shot) supports the mitochondrial energy systems that high-output training demands. It is not a peptide in the traditional sense, but it stacks with everything and addresses the cellular energy bottleneck that limits recovery.
Sexual Health
PT-141 / Bremelanotide ($250/month) works through a fundamentally different mechanism than medications like Viagra or Cialis. Those drugs work on blood flow. PT-141 works on the brain, activating melanocortin receptors in the hypothalamus that regulate sexual arousal and desire. This makes it effective for both men and women, and particularly useful when the issue is low desire or arousal rather than a mechanical blood flow problem.
PT-141 is often used alongside testosterone replacement therapy for patients where optimized hormones have improved energy and body composition but desire has not fully returned.
Sleep and Overall Optimization
Sermorelin ($250/month) administered before bed stimulates your body's natural growth hormone pulse during deep sleep. Growth hormone is released in pulses during slow-wave sleep, and Sermorelin amplifies this process. Patients consistently report deeper, more restorative sleep within the first 2-4 weeks. This is not a sedative. It works by enhancing a process your body already runs during sleep.
Cellular Energy and Longevity
NAD+ ($60/shot) is a coenzyme required for mitochondrial energy production, DNA repair, and sirtuin activation. NAD+ levels decline significantly with age, and that decline correlates with reduced energy, slower recovery, and impaired cellular repair. At $60 per injection, NAD+ is the most accessible entry point into optimization medicine and stacks with every peptide and hormone therapy we offer.
For a deeper dive on the science, read our full NAD+ evidence guide.
PEPTIDE COMPARISON TABLE
Every peptide we offer at Moonshot Medical, compared side by side. All compounds are pharmaceutical-grade from a licensed 503A compounding pharmacy and include medical oversight.
| Peptide | Category | Price | Best For | Frequency | Typical Cycle |
|---|---|---|---|---|---|
| BPC-157 | Tissue Repair | $250/mo | Tendons, ligaments, gut healing | Daily injection | 8-12 weeks |
| TB-500 | Tissue Repair | $250/mo | Systemic repair, muscle recovery | 2-3x per week | 8-12 weeks |
| Wolverine Blend | Tissue Repair | $375/mo | Comprehensive recovery (BPC + TB) | Daily injection | 8-12 weeks |
| GHK-Cu | Anti-Aging / Skin | $175/mo | Collagen, skin elasticity, fine lines | Daily injection | 3-6 months |
| Glow Stack | Anti-Aging / Skin | $400/mo | Full-spectrum anti-aging | Daily injection | 3-6 months |
| Sermorelin | Growth Hormone | $250/mo | Sleep, body comp, recovery | Nightly injection | 3-6 months |
| PT-141 | Sexual Health | $250/mo | Desire, arousal (men and women) | As needed | Ongoing |
| NAD+ | Cellular Energy | $60/shot | Energy, mitochondrial function, stacks with everything | 1-2x per week | Ongoing |
All pricing includes pharmaceutical-grade compounds, medical oversight, personalized dosing protocol, and monitoring. Insurance does not cover peptide therapy.
Not Sure Which Peptide Fits Your Goals?
Take our free 2-minute quiz and get a personalized recommendation based on your symptoms, goals, and budget.
Take the Free Peptide QuizBUDGET GUIDE
Budget matters. Here is an honest breakdown of what each price tier gets you.
Under $200/month
GHK-Cu ($175/month) is the most affordable monthly peptide protocol. Targets skin quality, collagen production, and anti-aging. A solid starting point if your primary concern is skin and appearance.
NAD+ ($60/shot) is the lowest-cost entry into optimization medicine. At 1-2 shots per week during a loading phase, you are looking at $240-480/month, but many patients maintain on 1-2 shots per month ($60-120). Stacks with everything else.
$200-$300/month
This is where most individual peptide protocols land. BPC-157, TB-500, Sermorelin, and PT-141 are all $250/month. Each targets a different system, so the choice depends entirely on your primary goal. Injury recovery? BPC-157 or TB-500. Sleep and body composition? Sermorelin. Sexual health? PT-141.
$300-$400/month
Wolverine Blend ($375/month) gives you BPC-157 and TB-500 combined. This is more cost-effective than running both separately and provides the broadest tissue repair coverage. Ideal for athletes, post-surgical patients, or anyone with significant recovery needs.
$400+ per month
Glow Stack ($400/month) is the comprehensive anti-aging protocol. At this tier, you can also start stacking multiple therapies: a recovery peptide plus NAD+, or a peptide protocol alongside TRT or BHRT. Multi-therapy protocols are where the compounding effects become significant, because you are addressing multiple systems simultaneously.
STACKING GUIDE: WHAT PAIRS WELL
Peptides that work through different biological pathways can be combined for greater effect. This is not theoretical. Certain combinations target complementary mechanisms and produce results that neither compound achieves alone. Here are the most effective stacks we use in practice.
BPC-157 + TB-500
The classic recovery stack (available pre-combined as the Wolverine Blend). BPC-157 provides localized repair through angiogenesis and growth factor upregulation. TB-500 provides systemic reach through actin upregulation and stem cell mobilization. Together they cover both local and systemic healing pathways.
GHK-Cu + BPC-157
GHK-Cu stimulates collagen synthesis and skin remodeling from the outside in. BPC-157 promotes connective tissue repair from the inside out. Combining them addresses skin quality, wound healing, and tissue integrity through complementary mechanisms. Particularly useful post-procedure or for patients with both skin concerns and underlying tissue damage.
Any Peptide + NAD+
NAD+ supports the cellular energy production that every other therapy depends on. Peptides send signals to repair, grow, and remodel tissue. But those processes require ATP. NAD+ ensures your mitochondria can deliver the energy those signals demand. This is why we call NAD+ a universal stacking partner.
Peptides + TRT/BHRT
Testosterone replacement and bioidentical hormone therapy optimize the hormonal environment. Peptides provide targeted therapeutic effects within that optimized environment. For example: TRT improves energy, body composition, and baseline recovery. Adding Sermorelin amplifies the growth hormone axis. Adding BPC-157 accelerates injury repair. The hormones set the foundation; the peptides build on it.
A note on stacking: More is not always better. Every additional compound adds cost and complexity. The goal is to identify the minimum effective protocol that addresses your primary goals. Start with one peptide, assess the response over 4-8 weeks, then add a second if needed. Your provider will help you sequence this correctly.
STILL NOT SURE WHICH PEPTIDE IS RIGHT FOR YOU?
Take our free 2-minute peptide quiz. Answer a few questions about your goals, health history, and budget, and get a personalized recommendation.
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Take the Free Peptide QuizCOMMON QUESTIONS
Which peptide is best for recovery?
It depends on the type of recovery. BPC-157 is the strongest option for tendon, ligament, and joint injuries. It promotes angiogenesis and upregulates growth factors at the injury site. TB-500 is better for systemic tissue repair and muscle recovery, working through actin upregulation and stem cell mobilization. The Wolverine Blend combines both for comprehensive healing. For general recovery from training, Sermorelin supports growth hormone release during sleep, which drives overnight repair.
Can I take multiple peptides at once?
Yes. Many peptides work through different biological pathways and can be safely combined. Common stacks include BPC-157 + TB-500 (the Wolverine Blend), GHK-Cu + BPC-157 for skin and connective tissue, and nearly any peptide + NAD+ for enhanced cellular energy. Your provider will design a protocol based on your goals, budget, and health history. Some combinations are more effective than others, and timing matters.
How do I know if peptide therapy is right for me?
Peptide therapy is most appropriate if you have a specific goal that peptides are designed to address: a nagging injury that is not healing, declining skin quality, sexual dysfunction, poor sleep quality, or a desire to optimize athletic recovery and body composition. You need a medical evaluation first. Peptides are prescription medications administered under medical supervision, not supplements you can self-prescribe. A consultation determines whether peptides fit your clinical picture and goals.
Are peptides safe?
Peptides used in clinical settings have favorable safety profiles when sourced from licensed 503A compounding pharmacies and administered under medical supervision. Most side effects are mild: injection site irritation, occasional flushing, or temporary fatigue. The biggest safety risk is not the peptides themselves but the source. Unregulated "research chemical" products sold online have no quality controls and may contain contaminants, incorrect doses, or entirely different compounds. Pharmaceutical-grade peptides from licensed pharmacies with proper medical oversight are a fundamentally different risk profile.
How much does peptide therapy cost?
At Moonshot Medical in Park Ridge, IL, peptide therapy ranges from $60 per shot for NAD+ to $400 per month for the Glow Stack. Most individual peptides (BPC-157, TB-500, Sermorelin, PT-141) are $250 per month. GHK-Cu is $175 per month. The Wolverine Blend (BPC-157 + TB-500) is $375 per month. All pricing includes pharmaceutical-grade compounds from a licensed 503A compounding pharmacy, medical oversight, personalized dosing, and monitoring. Insurance does not cover peptide therapy. See our full peptide pricing page for details.
PEPTIDE THERAPY IN PARK RIDGE & CHICAGO'S NORTHWEST SUBURBS
Moonshot Medical and Performance
542 Busse Hwy
Park Ridge, IL 60068
(224) 435-4280
- No referral needed -- book directly online
- In-person care -- not a telehealth peptide mill
- Pharmaceutical-grade -- licensed 503A compounding pharmacy
- Medical oversight -- personalized dosing and monitoring
Serving the Northwest Suburbs
Patients come to Moonshot for peptide therapy from across the northwest Chicago suburbs:
- Des Plaines, Niles, Edison Park
- Morton Grove, Glenview, Skokie
- Mount Prospect, Arlington Heights
- Rosemont, Norwood Park, Chicago
Minutes from O'Hare, right off the Kennedy Expressway. Free parking on-site.
READY TO START PEPTIDE THERAPY?
Book a consultation to discuss which peptide fits your goals, your health history, and your budget. Your provider will design a personalized protocol and monitor your progress.